4-phenyl-1-piperazinecarboxylic acid tert-butyl ester

4-phenyl-1-piperazinecarboxylic acid tert-butyl ester - Names and Identifiers

Name	1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimethylethyl ester
Synonyms	1-Boc-4-Phenylpiperazine N-(tert-Butoxycarbonyl)-N'-phenylpiperazine TERT-BUTYL 4-PHENYLPIPERAZINE-1-CARBOXYLATE Tert-Butyl 4-Phenylpiperazine-1-Carboxylate 4-Phenylpiperazine-1-carboxylic acid tert-butyl ester 4-phenyl-1-piperazinecarboxylic acid tert-butyl ester 1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-diMethylethyl ester 1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimethylethyl ester
CAS	77278-63-8

4-phenyl-1-piperazinecarboxylic acid tert-butyl ester - Physico-chemical Properties

Molecular Formula	C15H22N2O2
Molar Mass	262.35
Density	1.093±0.06 g/cm3(Predicted)
Melting Point	70-71℃
Boling Point	372.2±35.0 °C(Predicted)
pKa	3.29±0.10(Predicted)
Storage Condition	Room Temprature

4-phenyl-1-piperazinecarboxylic acid tert-butyl ester - Introduction

1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimethylethyl ester, chemical name 1-Piperazinecarboxylic acid, 4-phenyl-, 1,1-dimethylethyl ester, is an organic compound. Its structural formula is C17H24N2O2.

Nature:
1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimethylethyl ester is a solid, soluble in organic solvents such as chloroform, methylene chloride and dimethyl sulfoxide. It has low toxicity and can irritate the eyes and skin.

Use:
1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimenthylethyl ester is an important organic synthesis intermediate. It is commonly used in the synthesis of drugs, pesticides and other organic compounds. It has the role of protecting hydroxyl and amino groups and can be used to synthesize biologically active compounds.

Preparation Method:
The preparation method of 1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimenthylethyl ester is relatively simple. The tert-butoxycarbonyl group (Boc protecting group) is typically introduced using the reaction of 4-phenylpiperazine and tert-butyldimethylsilyl chloride, followed by removal of the protecting group by treatment with base to give the desired product.

Safety Information:
1-Piperazinecarboxylicacid, 4-phenyl-, 1,1-dimethylethyl ester is irritating. Care should be taken to avoid contact with skin and eyes, and personal protective equipment such as gloves and safety glasses should be used when necessary. During storage and handling, it should be kept in a sealed container, away from heat and ignition sources. Since it is an organic compound, follow laboratory safety regulations when using and handling it, and avoid mixing it with other chemicals to prevent dangerous reactions.

Last Update：2024-04-09 21:04:16